The complex of the Sacred Heart Institute of the Daughters of Charity of St. Vincent de Paul constitutes an interesting example of integration with the city, planned at the time when Cagliari was stitching together the urban and social fabric of the historic Villanova district with the expansion of the St. Benedict neighborhood between the beginning of the last century and the 1930s. The architectures, marked by great formal simplicity, are an interesting example of how Italian architecture between the 1930s and 1950s was able, even in minor works, to consciously and positively combine the paradigms of modern European architecture with the need to harmonize buildings with the historic fabric, without anachronisms but also without forcing geometries according to functionalist models. Particular attention is paid to the composition and placement of the Institute chapel, which has a single-nave structure with a side entrance on the left and a main front entrance. The interior of the building is completely frescoed by the painter Giovanni Bacicia Scano. There are three large painting-like frescoes on each side, three on the right side and three on the left side.