Milis is the last town in Campidano di Oristano, at the base of the foothills of the Montiferru mountain range. A transit area from lowland areas to northern Sardinia, it was permanently frequented from the Middle Bronze Age to the Byzantine period in the nuraghe Cobulas or Cuccuru de is Zanas. In the Judicial period several farms (domos) dependent on the Camaldolese monastery of Santa Maria di Bonarcado arose in Milis, including the first ones dedicated to citrus farming as recalled by the toponym “S’ortu e is Paras” in the tradition. In the center of Milis stands in the 15th century a government building of the Curatoria di Parte Milis of the Marquisate of Oristano; it then becomes a dwelling house, in the 17th century, in the Gothic-Aragonese style (Vacca or Vaca, or Vacha family), which then passes to the Pilo Boyl family of Putifigari, in the early 19th century, due to the marriage of General Vittorio with Maddalena Vacca Salazar.
Other significant historical buildings: the parish church of St. Sebastian, 16th century, St. Paul’s Church in the Romanesque style (1140-1220). The overlooking cemetery houses in a box the Italian-German War Cemetery of the fallen of World War II. On the outskirts of the town is the Pernis-Vacca Establishment, established in the early 1900s as a horse farm. Its vast garden, currently planted with citrus trees, was recently included among Sardinia’s seven historic gardens.