The town stands on a slight plateau on the slopes of the hills bordering Campidano to the east near the most important waterway (Riu Cardaxiu). The Campidanese plain begins to vary in the territory of Serrenti with a series of small hills where, at the border with Furtei, Mediterranean scrub, now replaces wheat and vine crops.
The area was already inhabited in Nuragic times, due to the presence in the territory of numerous nuraghi (“Bruncu Su Castiu” located on the edge of the S.S. 131, “Monti Mannu,” “Genna Serrenti” and “Cuccuru Turri” located in the hills north of the municipality). Near the present village are the ruins of ancient villages from the Roman period, at Gutturrosa, Sa Conca Manna and Santus Angius. During the Middle Ages it belonged to the giudicato of Cagliari and was part of the curatoria of Nuraminis. At the fall of the giudicato (1258) it came under Pisan rule and later, around 1355, under Aragonese rule. In Aragonese and Spanish times it divided fortunes with the other centers of the former curatoria. When Ludovico Bellit was created baron of Monastir in 1519, the village was annexed to the barony. Later (1355) it was granted as a fief by the King of Aragon Peter IV the Ceremonious to Francis of Valguarnera; in 1436, with the extinction of the lineage, it passed through the rule of various feudal families. In 1736, during the Savoy era, the town was under the lordship of the Simon and Ricca di Castelvecchio families, to whom it was redeemed in 1839 with the abolition of the feudal system, so it became a municipality administered by a mayor and town council.
