The church of Santa Rosalia was founded in the 15th century as a small oratory, vowed to Santa Rosalia by the city authorities for one of the recurrent plagues.
It is due to the Congregation of Sicilians, to whom the building was entrusted in 1695, the expansion and improvement of the religious structure, which was ceded in 1740 by the Congregation of Friars Minor Observant.
The facade is inspired by the lines of the Piedmontese Baroque.
In the second chapel, entering on the right, the relics of St. Savior of Horta were kept from 1844 to 1931, then placed in the high altar, renovated for the occasion by sculptor Andrea Usai.
For this reason the church is also known by the name of St. Savior, one of the dearest and most venerated saints by Sardinians.
Following the liturgical reform of the Second Vatican Council, the presbytery of the church was radically altered in 1967 with the insertion of an urn in the central altar, flanked by two Carrara marble angels by Roman sculptor Antonio Bellini, a large organ on the walls, and a mosaic decoration in the apse by Franco D’Urso.
A portico above Principe Amedeo Street connects the church façade to the building where the former convent was housed.